Taking LOKELMA

It is important that you take LOKELMA exactly as prescribed for as long as your doctor prescribes it.

If you have any questions about your prescription or dosing, please reach out to your healthcare provider or nurse right away.

When you fill your prescription, you will receive LOKELMA in individual, foil-lined packets.

If you are on dialysis treatment, learn more about taking LOKELMA here

Initial treatment for people not on dialysis

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Take one 10 g packet

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Three times a day

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For up to 48 hours

How to take LOKELMA

There are 3 steps to taking LOKELMA:

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Fill your cup with at least 3 tablespoons of water

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Empty the entire contents of the LOKELMA packet(s) into the cup

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Stir well and drink immediately. Don't worry—it's odorless and tasteless. If there is powder left, add more water, stir, and drink again

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LOKELMA can be taken with or without food

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People in the LOKELMA studies did not have to be on a low-potassium diet

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If you have been prescribed other oral medications, you may need to take LOKELMA 2 hours before or 2 hours after your medication

Talk to your healthcare provider to find out if you need to make any changes to your diet or timing of other medications.

Safety and Side Effects

Are there side effects when taking LOKELMA?

The most common side effect of LOKELMA is swelling in your body caused by fluid retention. Tell your doctor if you have any side effects that bother you or do not go away.

What is the most important thing I should know about LOKELMA?

LOKELMA can cause swelling (edema) caused by fluid retention in your body (such as hands, ankles, feet).

  • LOKELMA contains 400 mg of sodium in each 5 g dose. Watch for signs of swelling in your body especially if you limit sodium in your diet or are likely to have fluid retention in your body due to heart or kidney problems. Your doctor may tell you to reduce the sodium in your diet.
  • If you are not on dialysis, your doctor may also tell you to increase the dose of your diuretic.

If you are a hemodialysis patient:

  • Do not take LOKELMA on dialysis days.
  • Tell your doctor if you suddenly feel sick such as decreased oral intake of food or fluids or diarrhea, as you may be at risk of developing low levels of potassium in your blood while on LOKELMA; therefore, your dose of LOKELMA may need to be adjusted.

What should I tell my doctor before taking LOKELMA?

Before taking LOKELMA, tell your doctor about all your medical conditions, including

  • problems having a bowel movement, including severe constipation, a blockage (obstruction) in your bowel, or dry hard stool that will not pass out of your rectum (impaction).
  • problems with your bowels after surgery.