LOKELMA is a prescription medicine for adults with hyperkalemia (high potassium). It lowers your high potassium level and helps keep it in a normal range with continued use.

Hyperkalemia is a condition that can lead to serious and potentially life-threatening health issues.

LOKELMA works fast with potentially no changes to your current medications.* While taking LOKELMA, you may not be required to change your diet.*

Target Icon
Target Icon

It’s designed to target and remove potassium

Potassium Icon
Potassium Icon

It helps bring your potassium back to normal levels

Continuous Icon
Continuous Icon

It helps keep levels normal with continued use

No Smell Icon
No Smell Icon

It has no taste or smell

Hyperkalemia can be an ongoing condition that can be managed over time. It is important to keep taking LOKELMA as prescribed by your healthcare provider.

*In people who are not on dialysis.

People in the LOKELMA studies did not have to be on a low-potassium diet.

Why LOKELMA

Fast Delivery Icon
Fast Delivery Icon
It acts fast*

LOKELMA starts to bring your potassium levels down within 1 hour.

*In people who are not on dialysis.

Stable Icon
Stable Icon
It’s sustained

LOKELMA helps you maintain normal potassium levels with continued use, allowing you to manage your hyperkalemia.

Safety Icon
Safety Icon
It has few side effects

In studies involving more than 1700 people, LOKELMA was generally well tolerated, with few side effects.

Glass Icon
Glass Icon
It’s simple to take

LOKELMA is tasteless and odorless. It’s taken with just a glass of water.

*In people who are not on dialysis.

Talk to your healthcare provider about LOKELMA

Why LOKELMA is different

Binder Icon
Binder Icon

LOKELMA is a potassium binder. It works in the digestive tract where it binds potassium and removes it from the body so it doesn’t enter the bloodstream.

Target Icon
Target Icon

LOKELMA is designed to target and remove potassium and not calcium and magnesium.

Safety and Side Effects

Are there side effects when taking LOKELMA?

The most common side effect of LOKELMA is swelling in your body caused by fluid retention. Tell your healthcare provider if you have any side effects that bother you or do not go away.

What is the most important thing I should know about LOKELMA?

LOKELMA can cause swelling (edema) caused by fluid retention in your body (such as hands, ankles, feet).

  • LOKELMA contains 400 mg of sodium in each 5 g dose. Watch for signs of swelling in your body especially if you limit sodium in your diet or are likely to have fluid retention in your body due to heart or kidney problems. Your healthcare provider may tell you to reduce the sodium in your diet
  • If you are not on dialysis, your healthcare provider may also tell you to increase the dose of your diuretic
If you are a hemodialysis patient:
  • Do not take LOKELMA on dialysis days
  • Tell your healthcare provider if you suddenly feel sick such as decreased oral intake of food or fluids or diarrhea, as you may be at risk of developing low levels of potassium in your blood while on LOKELMA; therefore, your dose of LOKELMA may need to be adjusted
What should I tell my healthcare provider before taking LOKELMA?

Before taking LOKELMA, tell your healthcare provider about all your medical conditions, including

  • problems having a bowel movement, including severe constipation, a blockage (obstruction) in your bowel, or dry hard stool that will not pass out of your rectum (impaction)
  • problems with your bowels after surgery